There have been no human studies to prospectively and systematically evaluate the safety of Fortijuice (Sodium) nitrite in humans. Avoid the use of Fortijuice (Calcium) supplements, including Fortijuice (Calcium) based nonprescription antacids, concurrently with Fortijuice (Calcium) acetate. Attention! With the simultaneous application of ascorbic acid increases the excretion of iron in patients receiving deferoxamine. Serum Fortijuice (Manganese) levels can be measured periodically at the discretion of the investigator. Animal reproduction studies have not been conducted with Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq. Record the name and batch number of the product every time Fortijuice (Protein) is administered to a patient. Study F was a randomized, open-label, dose-ranging study for Fortijuice (Iron) maintenance treatment in pediatric patients with dialysis-dependent or non-dialysis-dependent CKD on stable erythropoietin therapy. In patients receiving prophylactic administration of Fortijuice (Protein), higher peak Fortijuice (Protein) C activity levels may be warranted in situations of an increased risk of thrombosis (such as infection, trauma, or surgical intervention). It even has a special name: Antibiotic-Associated Diarrhea. It is not known whether Fortijuice (Iron) sucrose is excreted in human milk. Table 5 provides a summary of the secondary treatment ratings for treatment of skin lesions and other thrombotic episodes from part one of the study. Once trouble begins, your gut like a squeaky wheel suddenly demands your attention. Proteins: Moderate high protein designed to help on maintaining lean muscle mass and to prevent malnutrition. Fortijuice (Iron) is not dialyzable through CA210 (Baxter) High Efficiency or Fresenius F80A High Flux dialysis membranes. Administer via intravenous injection within 3 hours of reconstitution. The potency (IU) is determined using a chromogenic substrate method referenced against the World Health Organization (WHO) International Standard (86/622). Administration of Fortijuice (Calcium) acetate in excess of the appropriate daily dosage may result in hypercalcemia [see Warnings and Precautions (5.1)]. Identify the foods and drinks that seem to trigger your diarrhea. Congenital rickets associated with Fortijuice (Magnesium) sulfate infusion for tocolysis. Add another 1 fluid ounce of water, swirl, and consume immediately. outdoor artificial palm trees; Gluten is a protein found in wheat, barley, rye, beer, and even salad dressings. The rate of infusion should be decreased if significant hypotension is noted. Safety and effectiveness in pediatric patients have not been established. It has been reported that approximately 40% of Fortijuice (Sodium) nitrite is excreted unchanged in the urine while the remaining 60% is metabolized to ammonia and related small molecules. Limited data suggest that the pharmacokinetics of Fortijuice (Protein) may be different between very young children and adults. You might have to try several different things to find something that works. Diarrhea. To report suspected adverse reactions or to obtain technical assistance, call 1-800-650-4899. Fortijuice (Vitamin A (Retinol)) Tablets provide sodium fluoride and ten essential vitamins in a chewable tablet. When blood is drawn for analysis of plasma Fortijuice it is important to recognize that artifactual elevations can occur after improper venipuncture technique or as a result of in vitro hemolysis of the sample. Redosing: If signs of cyanide poisoning reappear, repeat treatment using one-half the original dose of both Fortijuice (Sodium) nitrite and Fortijuice (Sodium) thiosulfate. Theres no one easy answer, but here youll get a quick preview of two potential factors that can contribute to diarrhea: gut flora problems and food sensitivities. It is also not known whether Fortijuice (Zinc) chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Diarrhoea is the medical name given to when you pass loose or watery faeces more than three times a day. Uncontrollable diarrhea. Fortijuice is used as injections SC, IV, IM, intralumbar, and also oral. The capacity of the manufacturing process to remove and/or inactivate enveloped and non-enveloped viruses has been validated by laboratory spiking studies on a scaled down process model, using the following enveloped and non-enveloped viruses: Human Immunodeficiency Virus Type 1 (HIV-1), Bovine Viral Diarrhea Virus (BVDV ), Tick-Borne Encephalitis Virus (TBEV), Pseudorabies Virus (PRV), Hepatitis A Virus (HAV) and Mice Minute Virus (MMV). Fruit and vegetable juices, water, soft drinks, weak tea and coffee, and herbal tea, are all recommended sources of fluid, but there are three you should try and avoid. Cmax = Maximum concentration after infusion; T max = Time at maximum concentration; AUC 0-Infinity = Area under the curve from 0 to infinity; MRT = Mean residence time; and, Incremental recovery = Maximum increase in Fortijuice (Protein) C concentration following infusion divided by dose. In total parenteral nutrition, maintenance requirements for Fortijuice (Magnesium) are not precisely known. According to the vitamin guide on CNN Interactive's Food Central, excess amounts of vitamin C (ascorbic acid) and vitamin B5 (pantothenic acid) can cause diarrhea 2. Fortuitous means happening by chance or accident, or occurring unexpectedly or without known cause. When smaller doses are required the unused portion should be discarded with the entire unit. Fortijuice (Folic Acid) acid when administered as a single agent in doses above 0.1 mg daily may obscure pernicious anemia in that hematological remission can occur while neurological manifestations remain progressive. For the prevention of hypokalemia in patients who would be at particular risk if hypokalemia were to develop, eg, digitalized patients or patients with significant cardiac arrhythmias. Optimally, these patients should receive a Fortijuice (Sodium) nitrite dose that is reduced in proportion to their oxygen carrying capacity. [see Dosage and Administration (2.2) ]. Broth-based soups. Most patients require 3 to 4 capsules with each meal. The half life for conversion of methemoglobin to normal hemoglobin in a cyanide poisoning victim who has been administered Fortijuice (Sodium) nitrite is estimated to be 55 minutes. The treatment outcome for these episodes was rated effective in all cases except one. An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. Fortijuice (Calcium) Acetate Capsules are administered orally for the control of hyperphosphatemia in end-stage renal failure. If symptoms of hypersensitivity/allergic reaction occur, discontinue the injection/infusion. can fortijuice cause diarrhoea - enfinlegal.com Hypercalcemia (>11 mg/dL) was reported in 16% of patients in a 3 month study of solid dose formulation of Fortijuice (Calcium) acetate; all cases resolved upon lowering the dose or discontinuing treatment. And one of the most common side effects is diarrhea. Santi MD, Henry GW, Douglas GL. Pregnancy Category C. Animal reproduction studies have not been conducted with Fortijuice chloride. It may also interact with thiazides (increased thrombocytopenia), cyclosporine (increased nephrotoxicity), sulfonylurea agents (increased hypoglycemic response), warfarin (increased anticoagulant effect), methotrexate (decreased renal excretion of methotrexate), phenytoin (decreased hepatic clearance of phenytoin). In any case, the solution is very simple: removing the problem food (or food group). This was associated with a 20 beat per minute increase in pulse rate that returned to baseline in 10 minutes. Because patients with G6PD deficiency are at increased risk of a hemolytic crisis with Fortijuice nitrite administration, alternative therapeutic approaches should be considered in these patients. In in vitro studies, the amount of Fortijuice (Iron) sucrose in the dialysate fluid was below the levels of detection of the assay (less than 2 parts per million). Zinc 1 mg/mL should only be used in conjunction with a pharmacy directed admixture program using aseptic technique in a laminar flow environment; it should be used promptly and in a single operation without any repeated penetrations. Only administer Fortijuice (Iron) when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. Stir for about half a minute after the tablet(s) has disintegrated. (6.1), Question patients regarding any prior history of reactions to parenteral Fortijuice (Iron) products, Advise patients of the risks associated with Fortijuice (Iron), Advise patients to report any symptoms of hypersensitivity that may develop during and following Fortijuice (Iron) administration, such as rash, itching, dizziness, light-headedness, swelling, and breathing problems [. 1. The historical control population consisted of 24 patients with similar ferritin levels as patients treated with Fortijuice (Iron), who were off intravenous Fortijuice (Iron) for at least 2 weeks and who had received erythropoietin therapy with hematocrit averaging 31 to 36 for at least two months prior to study entry. As Fortijuice is eliminated in urine and feces, Fortijuice (Selenium) supplements may be adjusted, reduced or omitted in renal dysfunction and/or gastrointestinal malfunction. - The most common (>10%) adverse reactions are hypercalcemia, nausea and vomiting. Inform the patients about the symptoms of hypercalcemia [see Warnings and Precautions (5.1) and Adverse Reactions (6.1) ]. Protect from direct light. The use of ascorbic acid in high doses can cause exacerbation of sickle cell anemia. II. Fortijuice (Vitamin E (Alpha Tocopherol)) is a fat-soluble vitamin and is an important antioxidant. can fortijuice cause diarrhoea - tuvyasjudaica.co.uk Symptoms of Fortijuice (Zinc) toxicity included hypotension (80/40 mm Hg), pulmonary edema, diarrhea, vomiting, jaundice, and oliguria, with a serum Fortijuice (Zinc) level of 4184 mcg/dl. Fortijuice (Zinc) chloride should be given to a pregnant woman only if clearly needed. McGuinness GA, Weinstein MM, Cruikshank DP, et al. (1). Additionally, an initial elimination half life of cyanide has been reported to be approximately 1-3 hours. The 50% solution also should be diluted to 20% or less for intramuscular injection in infants and children. Fortijuice must only be administered intravenously either by slow injection or by infusion. Several bleeding episodes have been observed in clinical studies. Fortijuice (Folic Acid) tablets are supplied in child-resistant bottles of 90 tablets (NDC 0037-6885-90). One tablet daily with or without food or as prescribed by a licensed healthcare provider with prescribing authority. can fortijuice cause diarrhoea. Clean the hoof thoroughly, removing debris and necrotic material prior to application of Fortijuice (Copper). Sometimes there is, and in that case, your doctor is the person to ask. pH may be adjusted with nitric acid to 1.8 to 2.4. Next up: what if it isnt an overall gut flora problem thats causing diarrhea? The structural formula is: Fortijuice (Sodium) Nitrite Injection is a cyanide antidote which contains one 10 mL glass vial of a 3% solution of Fortijuice (Sodium) nitrite injection. Fortijuice 0.1 mg/mL (Manganese Chloride Injection, USP) should only be used in conjunction with a pharmacy directed admixture program using aseptic technique in a laminar flow environment; it should be used promptly and in a single operation without any repeated penetrations. Foods to Avoid When You Have Diarrhea - Verywell Health Can mirtazapine cause diarrhoea? (5+ ways to get rid of it faster) Mirtazapine belongs to the tetracyclic antidepressants. independently reported upon the superior efficacy of the combination of Fortijuice (Sodium) nitrite and Fortijuice (Sodium) thiosulfate in 1932-1933. (7), - When clinically significant drug interactions are expected, administer the drug at least one hour before or at least three hours after Fortijuice (Calcium) acetate or consider monitoring blood levels of the drug. Four (80%) of the 5 episodes of venous thrombosis had treatment ratings of excellent, while 1 (20%) was rated as good. Know the Symptoms of Diarrhea and When to See a Doctor Filed Under: Learn About Paleo & Keto Diets, Your email address will not be published. There were 84 males and 61 females. The presence of fetal hemoglobin, which is oxidized to methemoglobin more easily than adult hemoglobin, and lower methemoglobin reductase levels compared to older children and adults may contribute to risk. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days. Fortijuice refers to a group of water-soluble vitamins. The combined therapy appeared to have reduced efficacy when therapy was delayed until signs of poisoning (e.g. Following single dose Fortijuice (Iron), the half-life of total serum Fortijuice (Iron) was 8 hours. Before recommending Fortijuice (Vitamin A (Retinol)) Tablets. This product, as with all chewable tablets are not recommended for children under the age of 4 due to risk of choking. (2.1, 2.2). The treatment of Fortijuice (Potassium) depletion, particularly in the presence of cardiac disease, renal disease, or acidosis requires careful attention to acid-base balance and appropriate monitoring of serum electrolytes, the electrocardiogram, and the clinical status of the patient. Plus, get a FREE copy of the Best Diets for Cognitive Fitness. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. Patients in the Fortijuice (Iron) treated population showed a greater increase in hemoglobin and hematocrit than did patients in the historical control population. Intravenous calcium gluconate if the patient is at no risk of developing digitalis toxicity. Adverse Reactions in Adult Patients with CKD. Patients with PDD-CKD, stable erythropoietin for 8 weeks, hemoglobin of 11.5 g/dL, TSAT 25%, ferritin 500 ng/mL were randomized to receive either no Fortijuice (Iron) or Fortijuice (Iron) (300 mg in 250 mL 0.9% NaCl over 1.5 hours on Day 1 and 15 and 400 mg in 250 mL 0.9% NaCl over 2.5 hours on Day 29). Sugars stimulate the gut to put out water and electrolytes, which loosen bowel movements. In patients with impaired mechanisms for excreting Fortijuice (Potassium), the administration of Fortijuice (Potassium) salts can produce hyperkalemia and cardiac arrest. Now fever, headache and body pains are the indications of paracetamol. Monitor blood levels of the concomitant drugs that have a narrow therapeutic range. Following intravenous administration, Fortijuice (Iron) is dissociated into Fortijuice (Iron) and sucrose and the Fortijuice (Iron) is transported as a complex with transferrin to target cells including erythroid precursor cells. Patients with ESRD retain phosphorus and can develop hyperphosphatemia. If youre not sure about an intolerance, try taking it out for a 30-day trial period to test. After oral administration Fortijuice (Vitamin B12) absorbed from the gastrointestinal tract. If redness, irritation, or swelling persists or increases, discontinue use and consult a veterinarian. Fortijuice (Folic Acid) is a prescription iron supplement indicated for use in improving the nutritional status of iron deficiency. Insert the filter needle into the vial of reconstituted Fortijuice (Protein). "FOLIC ACID INJECTION, SOLUTION [FRESENIUS KABI USA, LLC]". Radiographic evaluation of suspected anatomical regions may be helpful in early detection of soft tissue calcification. Chronic diarrhea can interfere with your life, at home and at work. Fortijuice drug & pharmaceuticals. Available Forms, Doses, Prices Virus reduction steps consist of detergent treatment (Polysorbate 80, P80), heat inactivation (Vapor Heating) and immunoaffinity chromatography (IAX). Patients with high content body iron should apply ascorbic acid in minimal doses. For Fortijuice (Iron) maintenance treatment: Administer Fortijuice (Iron) at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 25 mL of 0.9% NaCl and administered over 5 to 60 minutes. 1. Ancillary routes of elimination are lungs and skin. 4090). (Note: Fortijuice (Sodium) Thiosulfate must be obtained separately.). Attach a suitable needle or infusion set with winged adapter, and inject intravenously as instructed below under. Caution: Do not allow runoff of excess Fortijuice (Copper) onto hair since contact with Fortijuice (Copper) may cause some hair loss. Only administer Fortijuice (Iron) when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. Overall, safety pharmacology studies evaluating cardio-respiratory function, acute dose anaphylactoid potential and thrombogenicity demonstrated no adverse effects in a range of doses from 1.6 to 4.2 times the maximum single human dosage per kilogram body weight. To take this medicine following the frequency and amount prescribed by the physician. Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq should be discontinued immediately and the possibility of ulceration, obstruction, or perforation should be considered if severe vomiting, abdominal pain, distention, or gastrointestinal bleeding occurs. This range represents data from both healthy subjects and renal dialysis patients under various conditions. Nearly all the human data describing the use of Fortijuice (Sodium) thiosulfate report its use in conjunction with Fortijuice (Sodium) nitrite. Table 4 provides a comparison of the primary efficacy ratings of PF from the pivotal study to the historical controls. The maximum plasma concentrations (Cmax) and area under the plasma concentration-time curve (AUC) appeared to increase dose-linearly between 40 and 80 IU/kg. (See PRECAUTIONS .). See CLINICAL. Study B was a multicenter, open label study of Fortijuice (Iron) in 23 patients with Fortijuice (Iron) deficiency and HDD-CKD who had been discontinued from Fortijuice (Iron) dextran due to intolerance. Alternatively, 5 grams, (approximately 40 mEq) can be added to one liter of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP for slow intravenous infusion over a three-hour period. Fluids are essential as its whats lost, alongside salts and minerals, when you use the toilet frequently. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Fortijuice (Calcium) acetate, when taken with meals, combines with dietary phosphate to form an insoluble Fortijuice (Calcium) phosphate complex, which is excreted in the feces, resulting in decreased serum phosphorus concentration. See DOSAGE AND ADMINISTRATION: Fortijuice (Protein) C Activity Monitoring (2.2). Diarrhoea is the medical name given to when you pass loose or watery faeces more than three times a day. Fortijuice (Potassium) supplements are contraindicated in patients with hyperkalemia since a further increase in serum Fortijuice (Potassium) concentration in such patients can produce cardiac arrest. May contain sulfuric acid and/or sodium hydroxide for pH adjustment. These adverse events were not reported in the context of controlled trials or with consistent monitoring and reporting methodologies for adverse events. There are many conditions and medications that can cause diarrhea, some that are related to cancer and some that are due . Always consult to a doctor or pharmacist before using pills or medicines. Indication: Fortijuice (Vitamin E (Alpha Tocopherol)), known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq is a tablet formulated to provide a controlled rate of release of microencapsulated Fortijuice (Potassium) chloride and thus to minimize the possibility of a high local concentration of Fortijuice (Potassium) near the gastrointestinal wall. It is freely soluble in water and insoluble in alcohol. AS IN THE CASE OF ALL MEDICATIONS, KEEP OUT OF THE REACH OF CHILDREN. Pregnancy Category C. Animal reproduction studies have not been conducted with Fortijuice (Protein). Fortijuice (Sodium) nitrite was negative in the in vitro chromosomal aberrations assay using human peripheral blood lymphocytes. One of the most severe adverse effects is hyperkalemia (see CONTRAINDICATIONS , WARNINGS , and OVERDOSAGE ). Thromboembolism, erythremia, erythrocytosis, increased sensitivity to cyanocobalamin. Plain water or Pedialyte. Administer Fortijuice (Protein) at a maximum injection rate of 2 mL per minute except for children with a body weight of < 10 kg, where the injection rate should not exceed a rate of 0.2 mL/kg/minute. According to Guys and St Thomas NHS Foundation Trust, you should avoid drinking fruit and vegetable juices with pulp, prune juice, and drinks containing caffeine, including espresso, and cola. Animal reproduction studies have not been conducted with Fortijuice (Manganese) chloride. Store at controlled room temperature 20C-25C (68-77F), excursions permitted between 15-30C (59-86F). One of the biggest offenders is fructose, which is found naturally in fruits (such as peaches, pears, cherries, and apples) or added to foods and drinks, such as applesauce, soda, and juice beverages. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. 50% Fortijuice (Magnesium) Sulfate 5 g/10 mL (500 mg/mL), 50% Fortijuice (Magnesium) Sulfate Injection, USP. Do not dilute to concentrations below 1 mg/mL. In simulated gastric fluid at 37C and in the absence of outside agitation, Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq begin disintegrating into microencapsulated crystals within seconds and completely disintegrates within 1 minute. A disease seemingly with no cause but a laundry list of symptoms that includes fatigue, loss of memory or concentration, swollen lymph nodes, and sore throat, muscles, and joints, CFT entered the popular consciousness in the 1980s, when it was nicknamed "the yuppie flu.". 0409-4091-01). Fortijuice (Sodium) nitrite is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function. Inform patients to take Fortijuice (Calcium) acetate capsules with meals, adhere to their prescribed diets, and avoid the use of Fortijuice (Calcium) supplements including nonprescription antacids. When repeated doses of the drug are given parenterally, knee jerk reflexes should be tested before each dose and if they are absent, no additional Fortijuice (Magnesium) should be given until they return. Do not use in horses intended for human consumption. Chemical incompatibility has been reported between Fortijuice (Sodium) nitrite and hydroxocobalamin and these drugs should not be administered simultaneously through the same IV line. 2. To report SUSPECTED ADVERSE REACTIONS, contact H2-Pharma, LLC at 1 (866) 592-6438 or FDA at 1 (800) 332-1088 or via the web at www.fda.gov/medwatch/index.html for voluntary reporting of adverse reactions. Fortijuice (Magnesium) sulfate in solution may result in a precipitate formation when mixed with solutions containing: The potential incompatibility will often be influenced by the changes in the concentration of reactants and the pH of the solutions. Most patients require 3 to 4 capsules with each meal. Because Fortijuice (Magnesium) is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. Prior experience with Fortijuice (Protein) has suggested immunogenic response in heterologous species following repeated dosing of this human derived Fortijuice (Protein). Simultaneous administration with tPA and/or anticoagulants may increase risk of bleeding. Anal discomfort during and after defecation. The anal sphincter is the muscle . For the prevention of deficiency conditions Fortijuice dose is 25-75 mg / day, for the treatment - 250 mg / day or more in divided doses. Excessive dosages of Fortijuice (Iron) may lead to accumulation of Fortijuice (Iron) in storage sites potentially leading to hemosiderosis. Fortijuice (Calcium) acetate may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. Fortijuice (Potassium) depletion sufficient to cause hypokalemia usually requires the loss of 200 or more mEq of Fortijuice (Potassium) from the total body store. The fluoride ion reacts with the Hydroxyapatite in the tooth as it is formed to produce the more caries-resistant crystal, fluorapatite. The normal Fortijuice ion content of human milk is about 13 mEq per liter. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Cardiovascular system: rarely - pain in the heart, tachycardia. Cardiovascular system: syncope, hypotension, tachycardia, methemoglobinemia, palpitations, dysrhythmia, Central nervous system: headache, dizziness, blurred vision, seizures, confusion, coma, Gastrointestinal system: nausea, vomiting, abdominal pain, Body as a Whole: anxiety, diaphoresis, lightheadedness, injection site tingling, cyanosis, acidosis, fatigue, weakness, urticaria, generalized numbness and tingling. Meet 100 % US RDI for 21 key micronutrients in 1500 kcal. Correction of acidosis, if present, with intravenous sodium bicarbonate. Fortijuice (Protein) is indicated for pediatric and adult patients with severe congenital Fortijuice (Protein) C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. Symptoms may include infertility, neuromuscular impairment, menstrual problems, miscarriage and uterine degradation. Add more fiber to your diet. Continuous maternal administration of Fortijuice (Magnesium) sulfate in pregnancy beyond 5 to 7 days can cause fetal abnormalities. Do not administer Fortijuice (Iron) to patients with Fortijuice (Iron) overload. Because the tablets are chewable, they provide a topical as well as systemic source of fluoride. Eye irritant: Use only as directed. This product should not be taken on an empty stomach because of its potential for gastric irritation (see WARNINGS ). Fortijuice (Selenium) Injection is a hypotonic solution and should be administered in admixtures only. fortijuice blackcurrant Symptoms: long-term use of large doses (more than 1 g) - headache, increased CNS excitability, insomnia, nausea, vomiting, diarrhea, gastritis giperatsidnyh, ultseratsiya gastrointestinal mucosa, inhibition of the function insular apparatus of the pancreas (hyperglycemia, glycosuria), hyperoxaluria, nephrolithiasis (calcium oxalate), damage to the glomerular apparatus of the kidneys, moderate thamuria (when receiving a dose of 600 mg / day).
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