natural alternatives to isosorbide mononitrate

You need to take it every day in order for it to work. It has a very short duration of action and may not be suitable for some people. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Isosorbide mononitrate works in two ways. View all However, you should not flush this medication down the toilet. Mayo Clinic. Do not take two doses together to make up for a missed dose. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Many people using this medication do not have serious side effects. Do not store in the bathroom. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. This medicine is for you. PMC (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Take this medication by mouth as directed by your doctor, usually twice a day. Cardizem Alternatives Compared - Drugs.com Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. It is important that you follow the instructions your doctor gives to you about when to take your doses. Tachjian A, et al. Ask your doctor before using aspirin together with alcohol. Even if the medication is working, you may experience some unwanted side effects. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. The Swedish Multicentre Group. For details see our conditions. View interaction reports for isosorbide mononitrate and the medicines listed below. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Isosorbide mononitrate and isosorbide dinitrate - NHS Isosorbide mononitrate dose and side-effects info | Patient Bethesda, MD 20894, Web Policies Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. The narrowing makes it more difficult for blood to flow to your heart muscle. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Should I avoid certain foods while taking Isosorbide Mononitrate? Zhonghua Yi Xue Za Zhi (Taipei). What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. . Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. Please upgrade your browser or download modern browsers from here! Prescribed for Angina, Anal Fissure and Accessed Sept. 7, 2022. It works to relax your blood vessels. This is a condition where the heart does not beat as efficiently as it should. Isosorbide mononitrate systemic 60 mg (A ID). A single copy of these materials may be reprinted for noncommercial personal use only. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). The IR version can help treat and prevent angina. Never give it to other people even if their condition appears to be the same as yours. Moderately clinically significant. Read our editorial policy. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Make sure laboratory personnel and all your doctors know you use this drug. If you suffer headaches when taking Isosorbide mononitrate, be patient. Canada residents can call a provincial poison control center. Isosorbide mononitrate has an average rating of Store in a cool, dry place, away from direct heat and light. WebMD does not provide medical advice, diagnosis or treatment. Click here for an email preview. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. If you have any problems with the way your liver works, or any problems with the way your kidneys work. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Available for Android and iOS devices. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. MeSH Epub 2006 Mar 22. To provide you with the most relevant and helpful information, and understand which Highly clinically significant. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Last Revised - 09/15/2019. You can consult me online for homeopathic treatment. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Please see a good cardiologist, get admitted, get checked thoroughly. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). The .gov means its official. Do not let anyone else take your medication. These headaches may be a sign that the medication is working as it should. If headaches continue or become severe, tell your doctor promptly. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. http://www.upandaway.org. Isosorbide mononitrate helps to prevent angina chest pain from developing. Consult your pharmacist or local waste disposal company. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. Isosorbide Mononitrate ER Oral: Uses, Side Effects - WebMD Isosorbide mononitrate helps to prevent angina chest pain from developing. Change positions slowly until your body is used to the medication. Isosorbide dinitrate dose 30-120 mg daily in divided doses. 8600 Rockville Pike About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Herbal supplements can strongly affect the body. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. 88 ratings on Drugs.com. Talk to your pharmacist for more details. We study millions of patients and 5,000 more each day. Almost 70% of older adults use them. Instead, the best way to dispose of your medication is through a medicine take-back program. In: Current Medical Diagnosis & Treatment 2022. It is not intended as medical advice for individual conditions or treatment. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Diabetes treatment: Can cinnamon lower blood sugar? Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. Store at room temperature away from light and moisture. Compare a few possible alternatives below. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Headache is often a sign that this medication is working. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . Nitrates in the management of acute coronary syndrome. Natural Medicines. Copyright, 2023. Generic alternatives may be available. Does isosorbide mononitrate (Monoket) lower blood pressure? Before American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Isosorbide mononitrate belongs to the group of medicines called nitrates. Isosorbide mononitrate belongs to the group of medicines called nitrates. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. AskMayoExpert. Isosorbide may cause other side effects. The use of the Truven Health products is at your sole risk. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Disclaimer. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. But only about 25% of people who take herbal supplements tell their health care providers. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Does Isosorbide Mononitrate interact with other drugs you are taking? Drug information provided by: IBM Micromedex. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. This is called a medicine interaction. We study 23,548 Isosorbide mononitrate users. Isosorbide Mononitrate - Medicine.com Continue to take isosorbide even if you feel well. Do not take more or less of it or take it more often than prescribed by your doctor. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. FOIA The extended-release capsule usually is taken once daily. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. The information on this page is written and peer reviewed by qualified clinicians. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Dated October 2016. Does isosorbide mononitrate (Monoket) affect your kidneys? Natural Medicines. Sept. 26, 2022. privacy practices. [2] This drug may make you dizzy. What happens if I stop taking isosorbide mononitrate (Monoket)? 2005 - 2023 WebMD LLC. Isosorbide is in a class of medications called vasodilators. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. Try to keep your regular appointments with your doctor. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Take your next dose at the regular time. Consult your doctor before breast-feeding. This list covers only some interactions. Integrative medicine (complementary and alternative medicine). These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). Talk to your provider if you notice your chest pain starts to get worse. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. [2] It is taken by mouth. Methods: The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Usually avoid combinations; use it only under special circumstances. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Your doctor may tell you to take a pain reliever to treat your headaches. What are the side effects of Isosorbide Mononitrate ? You may report side effects to the FDA at 1-800-FDA-1088. This is not a complete list of possible side effects. 41% of reviewers reported a positive effect, while 50% reported a negative effect. In case of overdose, call the poison control helpline at 1-800-222-1222. Portions of this document last updated: Feb. 01, 2023. This content does not have an English version. There are 195 drugs known to interact with Natural remedies for depression: Are they effective? This content does not have an Arabic version. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. 19 are major, 174 are moderate, and 2 are minor. Saw palmetto. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. It can cause your blood pressure to become dangerously low. Natural Medicines. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. See the full pregnancy warnings document. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. https://naturalmedicines.therapeuticresearch.com. Ginkgo. It is important to take the drug at the same times each day. GoodRx works to make its website accessible to all, including those with disabilities. Aspirin has an average rating of Accessed Sept. 7, 2022. Liperoti R, et al. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. information is beneficial, we may combine your email and website usage information with Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. If you have recently had a head injury or a heart attack. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. The tablet usually is taken two or three times daily. Some of these medicine interactions can be risky. information and will only use or disclose that information as set forth in our notice of 67% of reviewers reported a positive effect, while 13% reported a negative effect. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. the unsubscribe link in the e-mail. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. Accessed Sept. 7, 2022. UpToDate Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. These side effects may go away during treatment as your body adjusts to the medicine. https://naturalmedicines.therapeuticresearch.com. You may opt-out of email communications at any time by clicking on Conclusions: An official website of the United States government. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. This risk may be even higher for certain groups. The extended-release tablet usually is taken once daily in the morning. Use of herbal products and potential interactions in patients with cardiovascular diseases. All rights reserved. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. This site needs JavaScript to work properly. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Which drugs or supplements interact with isosorbide mononitrate? It does not have such side effects. Do not double the dose to catch up. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg.